"We ourselves feel that what we are doing is just a drop in the ocean. But the ocean would be less because of that missing drop."
I am a research scientist specialising in CAR T-cell immunotherapy, with expertise spanning target discovery to in vivo efficacy assessment of gene and cell therapy products. My passion for translating immunotherapies into real-world treatments has led me to the biotech sector, where I develop assays to streamline the pathway from discovery to clinical application.
During my PhD, I developed a non-invasive quantitation method using SPECT/CT imaging to monitor and measure CAR T-cell infiltration in preclinical models. Before that, I worked at UCL Great Ormond Street Institute of Child Health, contributing to the development of T-cell-based therapies for childhood cancers.
I hold a BSc in Biotechnology from the University of Salamanca (Spain), having completed my final year at University of Melbourne (Australia) and an MRes in Molecular and Cellular BioSciences from Imperial College London.
I am passionate about scientific communication and enjoy sharing my research with both scientists and the public. If you're interested in my work or would like to connect, feel free to get in touch!
Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2
GPellizzari,O Martinez,S Crescioli,R Page [...],E Bugallo-Blanco, [...] SN Karagiannis
Journal for immunotherapy of cancer, 2021
Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients
S Abdul-Jawad, L Baù, T Alaguthurai, IDM Del Barrio, [...],E Bugallo-Blanco, [...] S IrshadCancer Cell,2 021
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
G Kildisiute, WM Kholosy, MD Young, K Roberts, [...],E Bugallo-Blanco, [...] K Straathof, S BehjatiScience Advances, 2021
Single cell derived mRNA signals across human kidney tumors .
Young D. M, Mitchell J T, Custers MC.A, Khanbirova E, Olver RW.T, Comitani F, Piapi A, Bugallo-Blanco E, Thevanesan C, Straahof K, Behjati S, et al.Nature Communications, 2021
A dynamic COVID-19 immune signature includes associations with poor prognosis
AG Laing, A Lorenc, IDM Del Barrio, A Das, M Fish, [...],E Bugallo-Blanco, [...] AC Hayday
Nature medicine, 2020
A consensus Covid-19 immune signature combines immuno-protection with discrete sepsis-like traits associated with poor prognosis
AG Laing, A Lorenc, IDM Del Barrio, A Das, M Fish, [...],E Bugallo-Blanco, [...] AC HaydayMedrxiv, 2020
Inducible GFP reporter permits visualisation of the activation status of tumour infiltrating CAR T cells using cryo-fluorescence tomography
European Molecular Imaging Meeting, Porto, 2024.
SEEING IS BELIEVING:Non-invasive imaging to quantify CAR T cell kinetics
European Molecular Imaging Meeting, Porto, 2024.
Development of an absolute quantitation method for genetically modified cell therapy
European Association for Cancer Research meeting, Torino, 2023.
No more shots in the dark: development of an absolute quantitation method for genetically modified cell therapy
The 17th European Molecular Imaging Meeting, Thessaloniki, 2022.
No more shots in the dark: Imaging and quantifying CAR T-cells [PDF]
Poster Prize, 2021 CRUK City of London Center Symposium, London, March 2021.
Next generation T-cell immunotherpay in neuroblastoma
UCL Institute of Child Health, London, December 2018.